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Insulin acts as an atypical KCNQ1/KCNE1-current activator and reverses long QT in insulin-resistant aged rats by accelerating the ventricular action potential repolarization through affecting the β -adrenergic receptor signaling pathway.
(Tıp Fakültesi, 2021-10-10)Insufficient-heart function is associated with myocardial insulin resistance in the elderly, particularly associated with long-QT, in a dependency on dysfunctional KCNQ1/KCNE1-channels. So, we aimed to examine the contribution ... -
The Effectiveness of Client-Centered Intervention With Telerehabilitation Method After Total Knee Arthroplasty.
(Tıp Fakültesi, 2021-08-22)There is known to be a decrease in quality of life and perceived occupational performance and satisfaction following total knee arthroplasty (TKA). This study was planned to examine the effectiveness of a client-centered ... -
Bimodal Effects of P2Y Antagonism on Matrix Metalloproteinase-Associated Contractile Dysfunction in İnsulin-Resistant Mammalian Heart.
(Tıp Fakültesi, 2021-07-16)The matrix metalloproteinases (MMPs) contribute to matrix remodeling in diabetes via tissue degradation; however, their contributions can be different depending on the pathology. For instance, MMPs are elevated in acute ... -
Glucagon-like peptide-1 receptor agonist treatment of high carbohydrate intake-induced metabolic syndrome provides pleiotropic effects on cardiac dysfunction through alleviations in electrical and intracellular Ca abnormalities and mitochondrial dysfunction.
(Tıp Fakültesi, 2021-09-14)The pleiotropic effects of glucagon-like peptide-1 receptor (GLP-1R) agonists on the heart have been recognised in obese or diabetic patients. However, little is known regarding the molecular mechanisms of these agonists ... -
Changes in the Anterior Lens Epithelium and Basement Membrane in Pseudoexfoliation Syndrome undergoing Surgery for Senile Cataracts: A Transmission Electron Microscopic Study.
(Tıp Fakültesi, 2021-11-01)Objective: To compare the electron microscopic lens findings with and without pseudoexfoliation syndrome (XFS), in patients undergoing surgery for senile cataract. Study Design: A descriptive study. Place and Duration of ... -
Variation of the Inferior Mesenteric Vein's Drainage Pattern and its Clinical Significance
(Tıp Fakültesi, 2021-06-18)The anatomical joining and drainage of the inferior mesenteric vein (IMV) into the splenic vein are usually reported in the anatomical literature. Nevertheless, the joining and drainage of IMV into the superior mesenteric ... -
Air transport of patients with critical cardiac conditions requiring intensive care.
(Tıp Fakültesi, 2021-08-01)It is extremely important that patients with severe heart disease who need an intensive care unit can be quickly transferred to advanced centers. Air transport is the fastest and safest way for doing this in these patients, ... -
A new approach to predicting shoulder dystocia: fetal clavicle measurement
(Sağlık Bilimleri Fakültesi, 2021-08-30)Background/aim: This study aimed to evaluate the relationship between second-and third-trimester clavicle lengths and birth weight and shoulder dystocia. Materials and methods: This prospective observational study included ... -
Coronavirus disease 2019 vaccine: An overview of the progression and current use
(Tıp Fakültesi, 2021-10-18)On December 31, 2019; unidentified pneumonia cases were reported from China. It was soon announced that these cases were of viral origin and the cause was a new coronavirus (CoV). Initially, the virus was called "novel ... -
Inguinofemoral lymphadenectomy and femoral dissection: cadaveric educational video
(Tıp Fakültesi, 2021-05-28)Vulvar cancer is rare. The complex inguinofemoral anatomy and the limited number of surgical procedures per year per gynecological oncologist tends to decrease the competency level. This step-by-step, cadaveric educational ... -
The effect of intracerebroventricular amyloid beta 1-42 application on cognitive functions in aged rats supplemented with taurine and the change of peroxisomal proteins in this process.
(Tıp Fakültesi, 2021-07-01)Objective: The aim of our study is to investigate the change of peroxisomal proteins in the neurodegenerative and oxidative process caused by the neurotoxicity of A beta 1 & ndash;42 in aged rats supplemented with taurine ... -
Effect of Propolis on Neurological Recovery After Experimental Spinal Cord Injury.
(Tıp Fakültesi, 2021)AIM: To examine the effect of propolis on the healing process in terms of both electrophysiological and ultrastructural parameters in a rat model of experimental spinal cord injury. MATERIAL and METHODS: Thirty rats ... -
Change in the geographic distribution of human resources for health in Turkey, 2002-2016.
(Tıp Fakültesi, 2021-04-01)Introduction: Turkey, which suffers from both undersupply of physicians, nurses and midwives and imbalanced distribution of healthcare personnel, has been developing and implementing various policies to solve these problems. ... -
Investigation of double-carbapenem efficiency in experimental sepsis of colistin-resistant .
(Tıp Fakültesi, 2021)OBJECTIVE: Klebsiella pneumoniae, a Gram-negative pathogen, especially which produces carbapenemase, is seen as a major threat to public health due to rapid plasmid-mediated spread of resistance and limited therapeutic ... -
Interferon-Gene Family Alterations Following the SARS-Cov Infection in Association with Iron Metabolism and Lymphoid Biology
(Tıp Fakültesi, 2021)Interferon (IFN) family has a significant impact on both SARS-CoV and SARS-CoV-2. The aim of this current bioinformatics study is to assess IFN-gene family alterations following the SARS-CoV infection in association with ... -
The role of labile Zn and Zn-transporters in the pathophysiology of mitochondria dysfunction in cardiomyocytes.
(Tıp Fakültesi, 2021-02-01)An important energy supplier of cardiomyocytes is mitochondria, similar to other mammalian cells. Studies have demonstrated that any defect in the normal processes controlled by mitochondria can lead to abnormal ROS ... -
Analysis of 3702 patients with acne vulgaris and concomitant comorbidities in Turkey: a multi-centered, prospective, controlled study.
(Tıp Fakültesi, 2021-05-01)Background Acne vulgaris is a chronic inflammatory skin disease that affects the pilosebaceous unit. Although it is considered to be a skin-limited disease, different clinical studies have recently been published in which ... -
Anticorrosive Properties of Green Silver Nanoparticles to Prevent Microbiologically Influenced Corrosion on Copper in the Marine Environment
(Tıp Fakültesi, 2021-03)Microbiologically influenced corrosion is a global problem especially materials used in marine engineering. In that respect, inhibitors are widely used to control fouling and corrosion in marine systems. Most techniques ... -
Assessing the genetic impact of Enterococcus faecalis infection on gastric cell line MKN74
(Tıp Fakültesi, 2021-01-27)Purpose Enterococcus faecalis (E. faecalis) is an important commensal microbiota member of the human gastrointestinal tract. It has been shown in many studies that infection rates with E. faecalis in gastric cancer ... -
The association between urinary BPA levels and medical equipment among pediatric intensive care patients.
(Ezcacılık Fakültesi, 2021-04-01)We aim to evaluate urinary total BPA (tBPA) levels and association with medical devices used on patients in pediatric intensive care units. This cross-sectional descriptive study included 117 critically ill children. Urinary ...
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